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acoustic_and_kinematic_analysis_of_speech_in_idiopathic_parkinson_s_disease [2014/03/15 12:58] (current)
bziolko created
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 +A. Bandini, F. Giovannelli, S. Orlandi, S.D. Barbagallo, M. Cincotta, P. Vanni, R. Chiaramonti, A. Borgheresi, G. Zaccara, C. Manfredi
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 +**Acoustic and kinematic analysis of speech in idiopathic Parkinson's disease**
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 +Institiutions: Università degli Studi di Firenze
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 +INTRODUCTION The main signs of Parkinson’s disease (PD) include impairments of voice and speech (hypokinetic dysarthria), which affect about 70% of patients. One of the most common speech impairments in PD is dysprosody, that includes alterations of rhythm and velocity of speech, velocity of articulation and speech/pause ratio.
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 +AIMS The aim of this study is to identify the presence of speech alterations in PD patients during a sentence repetition task, combining acoustic and kinematic analysis.
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 +METHODS 20 PD patients (age: 72.2 ± 8.6 years, disease duration: 7.2 ± 2.9 years, 14 male and 6 female and 17 healthy subjects (age: 68.5 ± 8.8 years, 7 male and 10 female) were audio-video registered during a sentence repetition task (repeating of a standardized Italian vocalic sentence at least 10 times, as spontaneously as possible, at comfortable loudness). Speech signals were acquired with Audacity software (version: 2.0.3), Shure SM58 microphone and Tascam US-144 board (sample frequency: 44.1 kHz). Video recordings were carried out by means the Microsoft kinect sensor, to perform automatic tracking of lips and jaw (in a 3D coordinate system). Audio analysis is based on a newly developed automatic voice-unvoice segmentation to calculate net speech rate (NSR) and the percentage of voiced segments with respect to the sentence duration (D). Video analysis consists in markerless tracking of lips and jaw movements in order to extract trajectories, speed and acceleration of the articulators and find correlations with acoustic parameters.
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 +RESULTS Preliminary results show a decrease of D in PD patients with a resulting increase in NSR. Video analysis is currently in progress as well as comparative analysis with UPDRS perceptive scale.
  
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